No. 1 . The diagram below represents human foetus in a uterus.
a) Name the part labeled S. (1 mark)
Chorion
b) (i) Name the types of blood vessels found in the structure labeled Q. (2 marks)
Arteries; veins
(ii) State the differences in composition of blood found in the vessels
named in (b)(i)above. (2 marks)
More food nutrients; more oxygen in veins less food nutrients more excretory
products in arteries
( c) Name two features that enable the structure labeled P carry out its
function. (2 marks)
Highly vascularized; large surface area
Presence of secretory cells
(d) State the role of the part labeled R (1 mark)
Cushion/ absorb shock
No. 2. (a) How is sex determined in man? (4 marks)
Males have two dissimilar chromosomes X and y/heterogametic;
Females have two similar chromosomes X and X/homogametic;
Male gamete/sperms have either X or y chromosome, while all ova have X chromosome;
if a sperm with X fuses with an ovum a female is formed and if a sperm with Y fuses with an ovum a male is formed;
(b) (i) Differentiate between sickle cell anaemia and sickle cell trait. (2 marks)
Sickle-cell trait is heterozygous while sickle cell anaemia is a homozygouscondition
(ii) Explain why people with sickle cell trait have an adaptive survival advantage over normal individuals in malaria endemic regions. (2 marks)
People with sickle cell trait are resistant to malaria; because the plasmodium cannot survive in sickle shaped red blood cells; reject: thrive for survive
No. 3. The diagram below represents bones at a joint found in the hind limb of a mammal.
(a) Name the bones labeled X,Y, and Z (3 marks)
X- Femur
Y- Tibia
Z- Fibula
(b) (i) Name the substance found in the place labeled W. (1 mark)
Synovial fluid
(ii) State the function of the substance named in (b) (i) above (1 mark)
Lubrication of the joint/ shock absorption
Distribution of pressure
(c) Name the structure that joins the bones together at the joint. (1 mark)
Ligament
(d) State the differences between ball and socket joint and the one illustrated in the diagram above. (1 mark)
Ball and socket joint allows movement in all planes while the illustrated allows movement in one plane only. Accept 3600 for all planes 1800 for one plane
(e) Name the structure at the elbow that performs the same function as the same function as the patella. (1 mark)
Olecranon process
No. 4. The diagram below represents some gaseous exchange structures in humans.
(a) Name the structures labeled K, L, and M . (3 marks)
K- Pleural membranes
L- Alveolus
M- Intercostal muscles
(b) How the structure labeled J is suited to its function? (3 marks)
Has C- shaped cartilage rings that support it preventing it from collapsing and allow free flow of air
Inner lining has mucus secreting cells that trap fine dust particles and microorganisms
Inner lining has hair like structures called cilia that enhance upward movement of the mucus to the larynx
(c) Name the process by which inhaled air moves from the structure labeled L into blood capillaries (1 mark)
Diffusion
(d) Give the scientific name of the organism that causes tuberculosis in humans (1 mark)
Mycobacterium tuberculosis (underline separately). Reject if not done so.
No. 5. A freshly obtained dandelion stem measuring 5 cm long was split lengthwise to obtain two similar pieces. The pieces were placed in solutions of different concentrations in petri dishes (L1 and L2) for 20 minutes. The appearance after 20 minutes is as shown
(a) Account for the appearance of the pieces in solutions L1 and L2 (6 marks)
L1 – Inner cells gained water by Osmosis; hence increased in length; epidermal cells did not gain water because they are covered by a water proof cuticle leading to curvature.
L2 – Inner cells lost water by osmosis; leading to (flaccidity) decrease in length; epidermal cells did not lose water due to waterproof leading to curvature
(b)State the significance of the biological process involved in the experiment (2 marks)
Absorption of water by the roots
Opening and closing of the stomata
No. 6.An experiment was carried out to investigate the effect of temperature on the rate of reaction catalyzed by an enzyme. The results are shown in the table below.
| Temperature (°C) | Rate of reaction in mg of products per unit time |
| 5 | 0.2 |
| 10 | 0.5 |
| 15 | 0.8 |
| 20 | 1.1 |
| 25 | 1.5 |
| 30 | 2.1 |
| 35 | 3.0 |
| 40 | 3.7 |
| 45 | 3.4 |
| 50 | 2.8 |
| 55 | 2.1 |
| 60 | 1.1 |
(a) On the grid provided draw a graph of rate of reaction against temperature. (6 marks)
(b) When was the rate of reaction 2.6 mg of product per unit time? (2 marks)
330C and 51.5 (± 0.50C)
32.5 – 33.5 and 51.0 – 52.0
(c) Account for the shape of the graph between
(i) 5°C and 40° C (2 marks)
As temperature is increased rate of reaction is increased/ more products are formed (per unit time) because enzymes become more active
(ii) 45° C and 60° C (3 marks)
As temperature increase rate of reaction decreases less/products are formed (unit per time) because enzymes become denatured by high temperatures above 400, hence cannot act on substrate.
(d) Other than temperature name two ways in which the rate of reaction between 5°C and 40°C could be increased. (2 marks)
Increase in enzyme and substance concentration
Use of cofactors and co-enxymes
(e) (i) Name one digestive enzyme in the human body which works best in acidic condition. (1 mark)
Pepsin,
Chymosin
Renin
(ii) How is the acidic condition for the enzyme named in (e) (i) above attained? (2 marks)
Wall of stomach/ gastric gland/ oxyntic/ pariental/ cell produced Hydrochloric
(f) The acidic conditions in (e) (ii) above is later neutralized
(i) Where does the neutralization take place? (1 mark)
Duodenum
(ii) Name the substance responsible for neutralization. (1 mark)
Bile juice/ e.g. NaHCO3
No. 7. Using a relevant example in each case, describe simple and conditional reflex actions.(20 marks)
Simple reflex action eg. withdrawal of finger from a sharp object/ hot object; its an automatic response to a specific stimulus; when the finger touches sharp object/ hot object, the pain receptors/ thermoreceptors in the skin are stimulants; and trigger off a nerve impulse; the nerve impulse is transmitted via the senses neurone; to the grey matter of the spinal cord/ CNS/ brain; the impulse is then transmitted via synapse; to the relay neurone; and then
through another synapse; to the motor neurone; and then through another synapse; to the motor neurone; the impulse is then transmitted to the effector muscles in the hand; (accept – efferent neurone for motor neurone; Afferent neurone for sense neurone; intermediate/ associative/ connector/interauncial neurone – for relay). The effector muscles/ biceps contract; and the finger is withdrawn from the hot object/ sharp object;
Conditioned reflex action – salivation in a dog/ human being (ace. any other relevant example) student in response to sound; it is an automatic response evoked from an animal by unrelated stimulus; substituted for the one which normally elicits the response; it develops from a past experience; and involves modification of behaviour/involves learning; it weakens with time; and must be reinforced by repeating the related stimulus; the dog/ student salivates when the bell (for meals) rings; because they have learnt to associate the ringing of the bell at meal time with food; everytime it rings (accept use of other relevant examples) they are offered food.
No. 8. Describe how a mammalian heart is structurally adapted to its function.(20 marks)
Cardiac muscles which contract and relax continually without fatigue/myogenic
Cardiac muscles are interconnected / a synclination form of network of fibres to rapidly and uniformly spread the contractions
Divided into four chambers for Atria to receive blood and ventricles to pump blood out of the heart
Divided into two sides by a longitudinal septum to prevent mixing of oxygenated and deoxygenated blood / for double circulation
Ventricles have thicker walls to generate high prevention pressure to pump blood
Wall of the left ventricle is thicker than that of right ventricle to pump blood over a long distance.
Have valves to prevent back flow of blood
Cuspid valves have strands of connective tissues / tendinious codes / valve tendons to prevent turning in/out during systole / when ventricles contract
Has coronary artery to nourish / supply oxygen to the heart/muscles; has a coronary vein to remove metabolic wastes carbon(iv)oxide
Enclosed by a pericardium to keep it in position / prevent over dilation
Pericardium secretes pericardial fluid to reduce friction / absorbs shock
Has Sino Artrio Node (SAN) which acts as a pacemaker
Has Atrio Ventricular Node (AVN) which relays contraction waves from SAN to the puncinje tissues
Has puncinje tissue / bundle of HIS to relay waves from AVN to the ventricular myocardium
Cardiac muscles have numerous mitochondria to generate energy for the muscular contractions
Has venacava and pulmonary vein to supply blood to the heart.
Has aorta and pulmonary artery to transport blood away from the heart.
